APRACUR DUO

This brand name is authorized in Brazil

Active ingredients

The drug APRACUR DUO contains a combination of these active pharmaceutical ingredients (APIs):

1 Metamizole sodium
UNII 6429L0L52Y - DIPYRONE

Metamizole sodium is a pyrazolone derivative with analgesic, antipyretic and slight antiinflammatory and spasmolytic properties. It has the most potent analgesic effect of all the pyrazolone derivatives. As with other analgesics, its mechanism of action has not been elucidated in detail. It includes inhibition of prostaglandin synthesis (PGE1 and PGE2) and reversible inhibition of platelet aggregation. It inhibits cyclo-oxygenase and influences the effect of arachidonic acid.

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2 Caffeine
UNII 3G6A5W338E - CAFFEINE

Caffeine is structurally related to the methylxanthines theophylline and theobromine. Caffeine’s main action is as a CNS stimulant.

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3 Chlorphenamine
UNII V1Q0O9OJ9Z - CHLORPHENIRAMINE MALEATE

Chlorphenamine is a potent antihistamine (H1-antagonist). Antihistamines diminish or abolish the actions of histamine in the body by competitive reversible blockade of histamine H1-receptor sites on tissues. Chlorphenamine also has anticholinergic activity.

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Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: BR Cรขmara de Regulaรงรฃo do Mercado de Medicamentos Identifier(s): 540920080043207, 540920080043307

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