AYVAKIT

This brand name is authorized in United States.

Active ingredients

The drug AYVAKIT contains one active pharmaceutical ingredient (API):

`1`	Avapritinib UNII `513P80B4YJ` - AVAPRITINIB
	Avapritinib is a Type 1 kinase inhibitor that has demonstrated biochemical in vitro activity on the PDGFRA D842V and KIT D816V mutants associated with resistance to imatinib, sunitinib and regorafenib with half maximal inhibitory concentrations (IC₅₀) of 0.24 nM and 0.27 nM, respectively, and greater potency against clinically relevant KIT exon 11, KIT exon 11/17 and KIT exon 17 mutants than against the KIT wild-type enzyme.
	Read more about Avapritinib

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
AYVAKIT Film-coated tablet	MPI, US: SPL/PLR	FDA, National Drug Code (US)

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
US	FDA, National Drug Code	72064-110, 72064-120, 72064-130

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