CO RASILEZ

This brand name is authorized in South Africa

Active ingredients

The drug CO RASILEZ contains a combination of these active pharmaceutical ingredients (APIs):

1 Aliskiren
UNII C8A0P8G029 - ALISKIREN HEMIFUMARATE

Aliskiren is an orally active, non-peptide, potent and selective direct inhibitor of human renin. By inhibiting the enzyme renin, aliskiren inhibits the RAAS at the point of activation, blocking the conversion of angiotensinogen to angiotensin I and decreasing levels of angiotensin I and angiotensin II.

Read about Aliskiren
2 Hydrochlorothiazide
UNII 0J48LPH2TH - HYDROCHLOROTHIAZIDE

Hydrochlorothiazide is a diuretic with antihypertensive properties. It acts by inhibiting the renal tubular re-absorption of sodium and chloride ions, which are excreted with an accompanying volume of water. Potassium excretion is also promoted.

Read about Hydrochlorothiazide

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
C09XA52 Aliskiren and hydrochlorothiazide C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09X Other agents acting on the renin-angiotensin system → C09XA Renin-inhibitors
Discover more medicines within C09XA52

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: ZA Health Products Regulatory Authority Identifier(s): 43/7.1.3/1099, 43/7.1.3/1101

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