This brand name is authorized in Cyprus, Ireland, New Zealand, United Kingdom
The drug FRUMIL contains a combination of these active pharmaceutical ingredients (APIs):
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1
Furosemide
UNII 7LXU5N7ZO5 - FUROSEMIDE
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Furosemide inhibits active chloride transport in the thick ascending limb. Re-absorption of sodium, chloride from the nephron is reduced and a hypotonic or isotonic urine produced. The evidence from many experimental studies suggests that furosemide acts along the entire nephron with the exception of the distal exchange site. |
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2
Amiloride
UNII 7M458Q65S3 - AMILORIDE HYDROCHLORIDE ANHYDROUS
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Amiloride has mild diuretic and anti-hypertensive activity. It acts primarily in the distal tubule and does not require aldosterone for its action. Amiloride is a mild natriuretic which does not initiate a concomitant decrease in potassium levels. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| FRUMIL Tablets | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C03EB01 | Furosemide and potassium-sparing agents | C Cardiovascular system → C03 Diuretics → C03E Diuretics and potassium-sparing agents in combination → C03EB High-ceiling diuretics and potassium-sparing agents |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 161825, 18255, 18281, 196935, 373948 |
| Country: IE | Health Products Regulatory Authority | Identifier(s): 25429, 25518, 25534 |
| Country: NZ | Medicines and Medical Devices Safety Authority | Identifier(s): 4166 |
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