This brand name is authorized in Austria, Brazil, Canada, Estonia, Spain, Finland, France, Croatia, Ireland, Israel, Italy, Lithuania, Netherlands, New Zealand, Poland, Romania, United Kingdom, United States
The drug ONCASPAR contains one active pharmaceutical ingredient (API):
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1
Pegaspargase
UNII 7D96IR0PPM - PEGASPARGASE
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Pegaspargase is a covalent conjugate of Escherichia coli-derived L-asparaginase with monomethoxypolyethylene glycol. The mechanism of action of L-asparaginase is the enzymatic cleavage of the amino acid L-asparagine into aspartic acid and ammonia. Depletion of L-asparagine in blood results in inhibition of protein-synthesis, DNA-synthesis and RNA-synthesis, especially in leukaemic blasts which are not able to synthesise L-asparagine, thus undergoing apoptosis. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| ONCASPAR Solution for injection/infusion | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01XX24 | Pegaspargase | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: BR | Câmara de Regulação do Mercado de Medicamentos | Identifier(s): 531319120009217, 540218100003317 |
| Country: CA | Health Products and Food Branch | Identifier(s): 02461900 |
| Country: EE | Ravimiamet | Identifier(s): 1187434, 1759361 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 1151070002 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 449842, 524351 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 61861579 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 378981 |
| Country: IL | מִשְׂרַד הַבְּרִיאוּת | Identifier(s): 8866 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 044702013, 044702025 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1079500, 1084699 |
| Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 148644 |
| Country: NZ | Medicines and Medical Devices Safety Authority | Identifier(s): 18738, 21439 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100362958, 100403746 |
| Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W66171001, W66172001 |
| Country: US | FDA, National Drug Code | Identifier(s): 72694-954 |
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