This brand name is authorized in Germany, Spain, Croatia, Ireland, United Kingdom
The drug TRIAPIN contains a combination of these active pharmaceutical ingredients (APIs):
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1
Felodipine
UNII OL961R6O2C - FELODIPINE
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Felodipine is a vascular selective calcium antagonist, which lowers arterial blood pressure by decreasing systemic vascular resistance. Felodipine is effective in all grades of hypertension. |
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2
Ramipril
UNII L35JN3I7SJ - RAMIPRIL
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Ramiprilat, the active metabolite of the prodrug ramipril, inhibits the enzyme dipeptidylcarboxypeptidase I (synonyms: angiotensin-converting enzyme; kininase II). In plasma and tissue this enzyme catalyses the conversion of angiotensin I to the active vasoconstrictor substance angiotensin II, as well as the breakdown of the active vasodilator bradykinin. Reduced angiotensin II formation and inhibition of bradykinin breakdown lead to vasodilatation. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| TRIAPIN Prolonged release tablet | Health Products Regulatory Authority (IE) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C09BB05 | Ramipril and felodipine | C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09B ACE inhibitors, combinations → C09BB ACE inhibitors and calcium channel blockers |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: DE | Bundesinstitut für Arzneimittel und Medizinprodukte | Identifier(s): 14016200, 15376840, 17836033, 17849194 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 62760 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 140112, 146850, 374047, 38880, 40934 |
| Country: IE | Health Products Regulatory Authority | Identifier(s): 50114, 50117, 50134, 50190, 72085 |
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