Breast cancer - monotherapy

Active Ingredient: Capecitabine

Indication for Capecitabine

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

Capecitabine is indicated for the treatment of as monotherapy for the treatment of patients with locally advanced or metastatic breast cancer after failure of taxanes and an anthracycline containing chemotherapy regimen or for whom further anthracycline therapy is not indicated.

For this indication, competent medicine agencies globally authorize below treatments:

1,250 mg/m² twice daily for 14 days followed by a 7-day rest period

For:

Dosage regimens

Oral, 1,250 milligrams capecitabine per square meter of body surface, 2 times daily to meals, 28 doses in total, over the duration of 21 days.

Detailed description

The recommended starting dose for capecitabine in the treatment of locally advanced or metastatic breast cancer is 1250 mg/m² administered twice daily (morning and evening; equivalent to 2500 mg/m² total daily dose) for 14 days followed by a 7-day rest period.

Dosage considerations

It should be taken with water within 30 minutes after a meal.

Active ingredient

Capecitabine

Capecitabine is a non-cytotoxic fluoropyrimidine carbamate, which functions as an orally administered precursor of the cytotoxic moiety 5-fluorouracil (5-FU). Capecitabine is activated via several enzymatic steps.

Read more about Capecitabine

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