Acute lymphoblastic leukaemia (ALL)

Active Ingredient: Idarubicin

Indication for Idarubicin

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

For second line treatment of relapsed acute lymphoblastic leukaemia (ALL).

For this indication, competent medicine agencies globally authorize below treatments:

10 mg/m² once daily for 3 days

Route of admnistration

Intravenous

Defined daily dose

10 - 10 mg per m² of body surface area (BSA)

Dosage regimen

From 10 To 10 mg per m² of body surface area (BSA) once every day for 3 day(s)

Detailed description

10 mg/m² i.v. daily for 3 days, as a single agent.

Active ingredient

Idarubicin

Idarubicin is a DNA intercalating anthracycline which interacts with the enzyme topoisomerase II and has an inhibitory effect on nucleic acid synthesis. Idarubicin has been shown to have a higher potency with respect to daunorubicin and to be an effective agent against murine leukaemia and lymphomas both by i.v. and oral routes.

Read more about Idarubicin

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