Ulcerative colitis

Indication for Sulfasalazine

Population group: Suitable for both men and women, only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

4-8 g in 4 divided doses daily

Route of admnistration


Defined daily dose

4 - 8 g

Dosage regimen

From 1 To 2 g 4 time(s) per day every day

Detailed description

Severe attacks: 1 to 2 g four times a day may be given in conjunction with steroids as part of an intensive management regime. Rapid passage of the suspension may reduce the effect of the drug.

The night time interval between doses should not exceed 8 hours.

Moderate attacks: 1 g four times a day may be taken with or without steroids.

Maintenance therapy: With induction of remission, reduce the dose gradually to 2 g per day. This dosage should be continued indefinitely, since discontinuance even several years after an acute attack is associated with a four-fold increase in relapse.

Active ingredient

Therapeutic benefit of sulfasalazine appears to be due to a local action of the sulfasalazine and its split product 5-aminosalicylic acid on the mucous membrane and deeper colonic structures.

Read more about Sulfasalazine

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