Paroxysmal supraventricular tachycardia

Active Ingredient: Verapamil

Indication for Verapamil

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)

The treatment and prophylaxis of paroxysmal supraventricular tachycardia and the reduction of the ventricular rate in atrial fibrillation/flutter. Verapamil should not be used for atrial fibrillation/flutter in patients with Wolff-Parkinson-White syndrome.

For this indication, competent medicine agencies globally authorize below treatments:

40-360 mg in 2-3 divided doses daily

Route of admnistration

Oral

Defined daily dose

40 - 360 mg

Dosage regimen

From 13.333 To 120 mg 3 time(s) per day every day

Detailed description

Up to 2 years: 20mg 2-3 times a day.

2 years and above: 40-120mg 2-3 times a day according to age and effectiveness.

0.1-0.3 mg/kg

Route of admnistration

Intravenous

Defined daily dose

0.1 - 0.3 mg per kg of body weight

Dosage regimen

From 0.1 To 0.3 mg per kg of body weight once every day

Detailed description

Verapamil must always be administered under ECG monitoring in young patients.

0-1 year: 0.1-0.2 mg/kg bodyweight (usual single dose range: 0.75-2 mg).

1-15 years: 0.1-0.3 mg/kg bodyweight (usual single dose range: 2-5 mg).

The dose may be repeated after 30 minutes if necessary. Many cases are controlled by doses at the lower end of the range. The injection should be stopped at the onset of the desired effect.

Active ingredient

Verapamil

Verapamil is a phenylalkylamine calcium antagonist which blocks the inward movement of calcium ions in cardiac muscle cells, in smooth muscle cells of the coronary and systemic arteries and in cells of the intracardiac conduction system. It lowers heart rate, increases myocardial perfusion and reduces coronary spasm. Because of its effect on the movement of calcium in the intracardiac conduction system, verapamil reduces automaticity, decreases conduction velocity and increases the refractory period.

Read more about Verapamil

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