Active Ingredient: Regadenoson
Regadenoson is a selective coronary vasodilator for use in adults as a pharmacological stress agent for the measurement of fractional flow reserve (FFR) of a single coronary artery stenosis during invasive coronary angiography, when repeated FFR measurements are not anticipated.
For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
400 - 400 ug
From 400 To 400 ug once every day for 1 day(s)
The recommended dose is a single injection of 400 micrograms regadenoson into a peripheral vein, with no dose adjustment necessary for body weight.
Patients should avoid consumption of any products containing methylxanthines (e.g. caffeine) as well as any medicinal products containing theophylline for at least 12 hours before regadenoson administration.
When possible, dipyridamole should be withheld for at least two days prior to regadenoson administration.
Aminophylline may be used to attenuate severe and/or persistent adverse reactions to regadenoson but should not be used solely for the purpose of terminating a seizure induced by regadenoson.
Regadenoson causes a rapid increase in heart rate. Patients should remain sitting or lying down and be monitored at frequent intervals after the injection until the ECG parameters, heart rate and blood pressure have returned to pre-dose levels.
This product is to be administered no more than twice, no less than10 minutes apart, during any 24 hour period. When administered twice 10 minutes apart in a 24-hour period, full safety data for the second injection of regadenoson are not available.
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