Prevention of gastroenteritis due to rotavirus infection

Active Ingredient: Rota virus

Indication for Rota virus

Population group: only infants (40 days - 1 year old)
Therapeutic intent: Preventive action

Rotavirus vaccine is indicated for the active immunisation of infants aged 6 to 24 weeks for prevention of gastroenteritis due to rotavirus infection.

For this indication, competent medicine agencies globally authorize below treatments:

1 ml once at the age of 6 weeks and thereafter 1 ml once at the age of 10-24 weeks

For:

Dosage regimens

Oral, 1 milliliters rota virus, once every 4 to 18 weeks, 2 doses in total.

Detailed description

The vaccination course consists of two doses. The first dose may be administered from the age of 6 weeks. There should be an interval of at least 4 weeks between doses. The vaccination course should preferably be given before 16 weeks of age, but must be completed by the age of 24 weeks.

Rotavirus vaccine may be given with the same posology to preterm infants born after at least 27 weeks of gestational age.

In clinical trials, spitting or regurgitation of the vaccine has rarely been observed and, under such circumstances, a replacement dose was not given. However, in the unlikely event that an infant spits out or regurgitates most of the vaccine dose, a single replacement dose may be given at the same vaccination visit.

It is recommended that infants who receive a first dose of rotavirus vaccine complete the 2-dose regimen. There are no data on safety, immunogenicity or efficacy when a specific rotavirus vaccine is administered for the first dose and another rotavirus vaccine is administered for the second dose.

Active ingredient

Rota virus

Rotavirus vaccine is indicated for the active immunisation of infants aged 6 to 24 weeks for prevention of gastroenteritis due to rotavirus infection. In clinical trials, efficacy was demonstrated against gastro-enteritis due to rotavirus of the most common genotypes G1P [8], G2P [4], G3P [8], G4P [8] and G9P [8].

Read more about Rota virus

Related medicines

Develop a tailored medication plan for your case, considering factors such as age, gender, and health history

Ask the Reasoner

Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.