Active Ingredient: Sertraline
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 50 milligrams sertraline, once daily, over the duration of 1 week. Afterwards, oral, between 50 milligrams sertraline and 200 milligrams sertraline, once daily. The maximum allowed total dose is 200 milligrams sertraline daily.
Sertraline treatment should be started at a dose of 50 mg/day.
Patients not responding to a 50 mg dose may benefit from dose increases. Dose changes should be made in steps of 50 mg at intervals of at least one week, up to a maximum of 200 mg/day. Changes in dose should not be made more frequently than once per week given the 24-hour elimination half life of sertraline.
The onset of therapeutic effect may be seen within 7 days. However, longer periods are usually necessary to demonstrate therapeutic response, especially in OCD.
Dosage during long-term therapy should be kept at the lowest effective level, with subsequent adjustment depending on therapeutic response.
Continued treatment in OCD should be evaluated regularly, as relapse prevention has not been shown for these disorders.
Sertraline should be administered once daily, either in the morning or evening.
Sertraline tablet can be administered with or without food.
For:
Oral, 50 milligrams sertraline, once daily, over the duration of 1 week. Afterwards, oral, between 50 milligrams sertraline and 200 milligrams sertraline, once daily. The maximum allowed total dose is 200 milligrams sertraline daily.
Initially 50 mg once daily.
Subsequent doses may be increased in case of less than desired response in 50 mg increments over a period of some weeks, as needed. The maximum dosage is 200 mg daily. However, the generally lower body weights of children compared to those of adults should be taken into consideration when increasing the dose from 50 mg. Dose changes should not occur at intervals of less than one week.
Sertraline should be administered once daily, either in the morning or evening.
Sertraline can be administered with or without food.
For:
Oral, 25 milligrams sertraline, once daily, over the duration of 1 week. Afterwards, oral, between 50 milligrams sertraline and 200 milligrams sertraline, once daily. The maximum allowed total dose is 200 milligrams sertraline daily.
Initially 25 mg once daily. The dosage may be increased to 50 mg once daily after one week.
Subsequent doses may be increased in case of less than desired response in 50 mg increments over a period of some weeks, as needed. The maximum dosage is 200 mg daily. However, the generally lower body weights of children compared to those of adults should be taken into consideration when increasing the dose from 50 mg. Dose changes should not occur at intervals of less than one week.
No data is available for children under 6 years of age.
Sertraline should be administered once daily, either in the morning or evening.
Sertraline can be administered with or without food.
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