Allergic rhinitis, urticaria

Active Ingredient: Desloratadine

Indication for Desloratadine

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Therapeutic intent: Curative procedure

Desloratadine is indicated in adults, adolescents and children over the age of 1 year for the relief of symptoms associated with:

  • allergic rhinitis
  • urticaria

For this indication, competent medicine agencies globally authorize below treatments:

5 mg once daily

For:

Dosage regimens

Oral, 5 milligrams desloratadine, once daily.

Detailed description

The recommended dose of desloratadine is 5 mg once a day.

Intermittent allergic rhinitis (presence of symptoms for less than 4 days per week or for less than 4 weeks) should be managed in accordance with the evaluation of patient's disease history and the treatment could be discontinued after symptoms are resolved and reinitiated upon their reappearance.

In persistent allergic rhinitis (presence of symptoms for 4 days or more per week and for more than 4 weeks), continued treatment may be proposed to the patients during the allergen exposure periods.

Dosage considerations

The dose can be taken with or without food.

For children 1-5 years old 1.25 mg once daily and for children 6-11 years old 2.5 mg once daily

For:

Dosage regimens

Regimen A, in case that patient age in years is ≥ 1 and patient age in years is ≤ 5

Oral, 1.25 milligrams desloratadine, once daily.

Regimen B, in case that patient age in years is ≥ 6

Oral, 2.5 milligrams desloratadine, once daily.

Detailed description

The prescriber should be aware that most cases of rhinitis below 2 years of age are of infectious origin and there are no data supporting the treatment of infectious rhinitis with desloratadine.

Children 1 through 5 years of age: 1.25 mg once a day.

Children 6 through 11 years of age: 2.5 mg once a day.

The safety and efficacy of desloratadine in children below the age of 1 year have not been established.

There is limited clinical trial efficacy experience with the use of desloratadine in children 1 through 11 years of age and adolescents 12 through 17 years of age.

Intermittent allergic rhinitis (presence of symptoms for less than 4 days per week or for less than 4 weeks) should be managed in accordance with the evaluation of patient's disease history and the treatment could be discontinued after symptoms are resolved and reinitiated upon their reappearance. In persistent allergic rhinitis (presence of symptoms for 4 days or more per week and for more than 4 weeks), continued treatment may be proposed to the patients during the allergen exposure periods.

Dosage considerations

The dose can be taken with or without food.

Active ingredient

Desloratadine

Desloratadine is a non-sedating, long-acting histamine antagonist with selective peripheral H1-receptor antagonist activity. After oral administration, desloratadine selectively blocks peripheral histamine Η1-receptors because the substance is excluded from entry to the central nervous system.

Read more about Desloratadine

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