Source: FDA, National Drug Code (US) Revision Year: 2020
LOKELMA is a powder for oral suspension. The active ingredient in LOKELMA is sodium zirconium cyclosilicate, a potassium binder. Sodium zirconium cyclosilicate is a non-absorbed zirconium silicate that preferentially exchanges potassium for hydrogen and sodium. LOKELMA is a odorless, insoluble white to grey powder for oral suspension. It has a mean particle size of 20 µm and includes no more than 3% of particles with a diameter below 3 µm. Each 5 g of sodium zirconium cyclosilicate contains 400 mg of sodium.
The chemical formula of sodium zirconium cyclosilicate is Na~1.5H~0.5ZrSi3O9•2–3H2O.
Figure 1. Crystal Structure of Sodium Zirconium Cyclosilicate:
| Dosage Forms and Strengths |
|---|
|
For oral suspension: 5 g or 10 g of white to grey powder in a foil-lined packet. |
| How Supplied | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
LOKELMA (sodium zirconium cyclosilicate) for oral suspension is supplied as a white to grey powder in foil-lined packets as follows:
|
| Drug | Countries | |
|---|---|---|
| LOKELMA | Austria, Canada, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Italy, Japan, Lithuania, Netherlands, Poland, Romania, United Kingdom, United States |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
