Source: FDA, National Drug Code (US) Revision Year: 2020
TOBRADEX (tobramycin and dexamethasone ophthalmic suspension) is a sterile, multiple dose antibiotic and steroid combination for topical ophthalmic use.
The chemical structures for tobramycin and dexamethasone are presented below:
Tobramycin:
Empirical Formula: C18H37N5O9
Chemical Name: O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→4)O[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl(1→6)]-2-deoxy-L-streptamine
Molecular Weight: 467.52
Dexamethasone:
Empirical Formula: C22H29FO5
Chemical Name: 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
Molecular Weight:392.47
Each mL of TOBRADEX (tobramycin and dexamethasone ophthalmic suspension) contains:
Actives: tobramycin 0.3% (3 mg) and dexamethasone 0.1% (1 mg).
Preservative: benzalkonium chloride 0.01%.
Inactives: tyloxapol, edetate disodium, sodium chloride, hydroxyethyl cellulose, sodium sulfate, sulfuric acid and/or sodium hydroxide (to adjust pH) and purified water.
| How Supplied |
|---|
|
Sterile ophthalmic suspension in 2.5 mL (NDC 0065-0647-25), 5 mL (NDC 0065-0647-05) and 10 mL (NDC 0065-0647-10) dispensers. Distributed by: Novartis Pharmaceuticals Corporation, East Hanover, New Jersey 07936 |
| Drug | Countries | |
|---|---|---|
| TOBRADEX | Austria, Brazil, Canada, Cyprus, Ecuador, Estonia, Spain, France, Hong Kong, Croatia, Lithuania, Malta, Mexico, Nigeria, Netherlands, New Zealand, Poland, Romania, Singapore, Tunisia, Turkey, United Kingdom, United States, South Africa |
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