Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2023 Publisher: Aventis Pharma Limited, 410 Thames Valley Park Drive, Reading, Berkshire, RG6 1PTUK Trading as: Sanofi, 410 Thames Valley Park Drive, Reading, Berkshire, RG6 1PT, UK
Rifinah 150/100 mg Tablets.
| Pharmaceutical Form |
|---|
|
Coated tablet. Cyclamen, smooth, shiny, round, curved sugar coated tablet. |
Active substances (per tablet):
Rifampicin 150 mg
Isoniazid 100 mg
Excipients with known effect (per tablet):
Sucrose 110.06 mg
For a full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Isoniazid |
Isoniazid is used mainly in the treatment of pulmonary tuberculosis but it appears to be effective also in the treatment of extrapulmonary lesions, including meningitis and genito-urinary disease. |
|
| Rifampicin |
Rifampicin is an active bactericidial antituberculosis drug which is particularly active against the rapidly growing extracellular organisms and also has bactericidial activity intracellularly. Rifampicin inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme. |
|
| Rifampicin and Isoniazid |
Rifampicin and isoniazid are active bactericidial antituberculosis drugs which are particularly active against the rapidly growing extracellular organisms and also have bactericidal activity intracellularly. Rifampicin has activity against slow- and intermittently-growing M. tuberculosis. Isoniazid acts against actively growing tubercle bacilli. |
| List of Excipients |
|---|
|
Tablet core: Sodium lauryl sulphate Sugar coating: Acacia |
Blister packs of 84 tablets (4 week calendar packs) in cardboard cartons.
Blister material is PVC/PVDC and aluminium foil/PVC.
Aventis Pharma Limited, 410 Thames Valley Park Drive, Reading, Berkshire, RG6 1PTUK
Trading as: Sanofi, 410 Thames Valley Park Drive, Reading, Berkshire, RG6 1PT, UK
PL 04425/0041
Date of First Authorisation: 15 December 1974
Date of latest renewal: 26 January 2005
| Drug | Countries | |
|---|---|---|
| RIFINAH | Spain, France, Hong Kong, Ireland, Malta, Netherlands, New Zealand, United Kingdom, South Africa |
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