Piriton Allergy Tablets (2012)
The tablets are indicated for symptomatic control of all allergic conditions responsive to antihistamines, including hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy, drug and serum reactions, insect bites.
Also indicated for the symptomatic relief of itch associated with chickenpox.
Posology and method of administration
Oral Administration only.
Do not exceed the stated dose or frequency of dosing.
Adults and children over 12 years: 1 tablet 4 to 6 hourly.
Maximum daily dose: 6 tablets (24mg) in any 24 hours.
Elderly: The elderly are more likely to experience neurological anticholinergic effects. Consideration should be given to using a lower daily dose (e.g. a maximum of 12mg in any 24 hours).
Children aged 6 – 12 years: ½ tablet 4 to 6 hourly.
Maximum daily dose: 3 tablets (12mg) in any 24 hours.
Not recommended for children under the age of 6 years.
Symptoms and signs
The estimated lethal dose of chlorphenamine is 25 to 50mg/kg body weight. Symptoms and signs include sedation, paradoxical excitation of the CNS, toxic psychosis, convulsions, apnoea, anticholinergic effects, dystonic reactions and cardiovascular collapse including arrhythmias.
Symptomatic and supportive measures should be provided with special attention to cardiac, respiratory, renal and hepatic functions and fluid and electrolyte balance. If overdosage is by the oral route, treatment with activated charcoal should be considered provided there are no contraindications for use and the overdose has been taken recently (treatment is most effective if given within an hour of ingestion). Treat hypotension and arrhythmias vigorously. CNS convulsions may be treated with i.v. diazepam. Haemoperfusion may be used in severe cases.
Special precautions for storage
Store below 30°C.
Nature and contents of container
The tablets are blister packed and supplied in cartons of 30 or 60 tablets.
Special precautions for disposal and other handling
For detailed instructions for use refer to the Patient Information Leaflet in every pack.