DEPONIT Transdermal patch Ref.[27650] Active ingredients: Glyceryl trinitrate

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2019  Publisher: Norgine Pharmaceuticals Limited, Norgine House, Widewater place, Moorhall Road, Harefield, Middlesex, U89 6NS, UK

Product name and form

Deponit 5 mg/24 h transdermal patch.

Pharmaceutical Form

Transdermal patch.

White, translucent square patch with convex round corners with “Deponit 5” marked on the outer face.

Qualitative and quantitative composition

One patch contains glyceryl trinitrate 18.7 mg.

The average amount of glyceryl trinitrate absorbed from each patch in 24 hours is 5 mg.

For the full list of excipients, see section 6.1.

Active Ingredient Description
Glyceryl trinitrate

Glyceryl trinitrate is a vasodilator and is used for angina of effort. Vasodilation is achieved by the releasing of free redical nitric oxide which activates guanylate cyclase and increases synthesis of guanosine 3′ and 5′-monophosphate with resultant effects on the phosphorylation of proteins in smooth muscle. If taken in excess, its vasodilatory effect can cause headache.

List of Excipients

Acrylate/vinyl acetate copolymer (adhesive matrix)
Polypropylene (backing foil)
Polyethylene (siliconised release liner)

Pack sizes and marketing

Multilaminate film/foil pouch with heat-sealed edges.

28 patches per carton.

Marketing authorization holder

Norgine Pharmaceuticals Limited, Norgine House, Widewater place, Moorhall Road, Harefield, Middlesex, U89 6NS, UK

Marketing authorization dates and numbers

PL 20011/0044

Date of latest renewal: 28 February 2008

Drugs

Drug Countries
DEPONIT Finland, Italy, Netherlands, Turkey, United Kingdom

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