CAPOTEN Tablets (2017)
Active ingredients: Captopril
Product Name and Form
Capoten 25 mg Tablets.
White, slightly mottled, square, biconvex tablet, with “25” embossed on one side and cross scored on the other side.
The score line is to facilitate breaking for ease of swallowing and to divide into equal doses of 12.5mg (half tablet) or 6.25mg (quarter tablet).
Qualitative and Quantitative Composition
Each tablet contains 25 mg captopril.
Excipient(s) with known effect: Lactose monohydrate
For the full list of excipients, see section 6.1.
Captopril is a highly specific, competitive inhibitor of angiotensin-I converting enzyme (ACE inhibitors). Inhibition of ACE results in decreased plasma angiotensin-II, which leads to decreased vasopressor activity and to reduced aldosterone secretion. In patients with hypertension, captopril causes a reduction in supine and erect blood pressure, without inducing any compensatory increase in heart rate, nor water and sodium retention.
Pack sizes and Marketing
The tablets are packaged in PVC/aluminium blisters or PVC/PVdC/aluminium blisters in packs of 28 or 84 tablets.
Not all pack sizes may be marketed.
E.R. Squibb & Sons Limited, Uxbridge Business Park, Sanderson Road, Uxbridge, Middlesex UB8 1DH
Date of first authorisation: 27th March 1981
Date of latest renewal: 26th November 1996