Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2021 Publisher: Neon Healthcare Limited, 8 The Chase, John Tate Road, Hertford, SG13 7NN, United Kingdom
Pharmacotherapeutic group: Mineral supplements: Calcium
ATC-code: A12AA04
An adequate intake of calcium is of importance during growth, pregnancy and breastfeeding.
The amount of calcium absorbed through the gastrointestinal tract is approximately 30% of the swallowed dose.
99% of the calcium in the body is concentrated in the hard structure of bones and teeth. The remaining 1% is present in the intra- and extracellular fluids. About 50% of the total blood-calcium content is in the physiologically active ionised form with approximately 10% being complexed to citrate, phosphate or other anions, the remaining 40% being bound to proteins, principally albumin.
Calcium is eliminated through faeces, urine and sweat. Renal excretion depends on glomerular filtration and calcium tubular reabsorption.
There is no information of relevance to the safety assessment in addition to what is stated in other parts of the SmPC.
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