MINITRAN 5 Adhesive transdermal patch Ref.[7279] Active ingredients: Glyceryl trinitrate

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2018  Publisher: Mylan Products Ltd, Station Close, Potters Bar, Hertfordshire, EN6 1TL, United Kingdom

Product name and form

Minitran 5 mg/24 h, transdermal patch.

Pharmaceutical Form

Adhesive transdermal patch.

Qualitative and quantitative composition

Minitran 5 has a surface area of 6.7 sq cm and contains 18 mg of glyceryl trinitrate. The average amount delivered in 24 hours is 5 mg.

For the full list of excipients, see section 6.1

Active Ingredient Description
Glyceryl trinitrate

Glyceryl trinitrate is a vasodilator and is used for angina of effort. Vasodilation is achieved by the releasing of free redical nitric oxide which activates guanylate cyclase and increases synthesis of guanosine 3′ and 5′-monophosphate with resultant effects on the phosphorylation of proteins in smooth muscle. If taken in excess, its vasodilatory effect can cause headache.

List of Excipients

Isooctyl acrylate/Acrylamide copolymer (93:7)
Ethyl oleate BP
Glyceryl monolaurate
Low density polyethylene film
One side silicone coated polyester film

Pack sizes and marketing

Each patch is individually packed in a heat sealed foil sachet. Cartons contain 30 patches.

Marketing authorization holder

Mylan Products Ltd, Station Close, Potters Bar, Hertfordshire, EN6 1TL, United Kingdom

Marketing authorization dates and numbers

PL 46302/0177

28 February 1999 / 7 December 2005

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