Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2016 Publisher: Kyowa Kirin Ltd, Galabank Business Park, Galashiels, TD1 1QH, UK
Rectogesic 4 mg/g Rectal Ointment.
| Pharmaceutical Form |
|---|
|
Rectal ointment. Off-white smooth opaque ointment formulation. |
Glyceryl trinitrate: 4 mg/g.
One gram of rectal ointment contains 4 mg Glyceryl trinitrate (GTN). The delivered dose from 375 mg of this formulation is approximately 1.5 mg GTN.
Excipient(s) with known effect:
The ointment also contains 36 mg Propylene Glycol, and 140 mg Lanolin, per gram rectal ointment.
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Glyceryl trinitrate |
Glyceryl trinitrate is a vasodilator and is used for angina of effort. Vasodilation is achieved by the releasing of free redical nitric oxide which activates guanylate cyclase and increases synthesis of guanosine 3′ and 5′-monophosphate with resultant effects on the phosphorylation of proteins in smooth muscle. If taken in excess, its vasodilatory effect can cause headache. |
| List of Excipients |
|---|
|
Propylene glycol |
30 g.
Aluminium tubes with white polyethylene non-piercing screw caps.
Kyowa Kirin Ltd, Galabank Business Park, Galashiels, TD1 1QH, UK
PL 16508/0037
28/08/2009
| Drug | Countries | |
|---|---|---|
| RECTOGESIC | Cyprus, Estonia, Spain, Finland, France, Ireland, Israel, New Zealand, Singapore, Turkey, United Kingdom |
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