Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2021 Publisher: Aventis Pharma Limited, 410 Thames Valley Park Drive, Reading, Berkshire, RG6 1PT, UK Trading as: Sanofi, 410 Thames Valley Park Drive, Reading, Berkshire, RG6 1PT, UK
Ikorel 10 mg Tablets
or
Nicorandil 10 mg Tablets.
| Pharmaceutical Form |
|---|
|
Tablets. Off-white, round tablets with facetted edge, scored on one side and with inscription “IK10” on the other side. The tablet can be divided into equal doses. |
Each tablet contains 10 mg nicorandil.
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Nicorandil |
Nicorandil is a derivative of the niacinamide that is structurally combined with an organic nitrate. It provides a dual mode of action leading to relaxation of vascular smooth muscle. Nicorandil is a potassium-channel opener that causes vasodilatation of arterioles and large coronary arteries. Its nitrate-like properties produce venous vasodilation through stimulation of guanylate cyclase. Nicorandil has a direct effect on coronary arteries without leading to a steal phenomenon. The overall action improves blood flow to post-stenotic regions and the oxygen balance in the myocardium. |
| List of Excipients |
|---|
|
Maize starch |
For each blister strip, there are:
Each cavity containing an Ikorel tablet is connected with the desiccant capsule by a channel.
The desiccant capsule must not be swallowed.
The blister pack is sealed with the aluminium cover foil on the removal side.
Pack sizes available are: 30 or 60 tablets.
Not all pack sizes may be marketed.
Aventis Pharma Limited, 410 Thames Valley Park Drive, Reading, Berkshire, RG6 1PT, UK
Trading as: Sanofi, 410 Thames Valley Park Drive, Reading, Berkshire, RG6 1PT, UK
PL 04425/0327
Date of first authorisation: 12 August 1992
Date of latest renewal: 06 May 2005
| Drug | Countries | |
|---|---|---|
| IKOREL | Australia, France, Ireland, Netherlands, New Zealand, Turkey, United Kingdom |
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