PALUDRINE Tablet Ref.[9545] Active ingredients: Proguanil

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2016  Publisher: Alliance Pharmaceuticals Limited, Avonbridge House, Bath Road, Chippenham, Wiltshire, SN15 2BB, United Kingdom

Product name and form

Paludrine 100 mg tablets.

Pharmaceutical Form

Tablet.

Scored, uncoated white tablet.

The tablet can be divided into equal halves.

Qualitative and quantitative composition

Proguanil hydrochloride 100 mg.

For the full list of excipients, see section 6.1.

Active Ingredient Description
Proguanil

Proguanil is an antimalarial drug and dihydrofolate reductase inhibitor. It acts like the other antifolate antimalarials by interfering with the folic-folinic acid systems and thus exerts its effect mainly at the time the nucleus is dividing. Proguanil is effective against the exoerythrocytic forms of some strains of plasmodium falciparum but it has little or no activity against the exoerythrocytic forms of p. Vivax.

List of Excipients

Calcium carbonate
Gelatin
Magnesium stearate (E572)
Maize starch

Pack sizes and marketing

HDPE bottles (100) and blister packs (98).

Marketing authorization holder

Alliance Pharmaceuticals Limited, Avonbridge House, Bath Road, Chippenham, Wiltshire, SN15 2BB, United Kingdom

Marketing authorization dates and numbers

PL 16853/0144

24/10/2005

Drugs

Drug Countries
PALUDRINE Nigeria, Netherlands, United Kingdom

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