HANIXOL Tablet Ref.[49879] Active ingredients: Mercaptopurine

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2020  Publisher: Fontus Health Ltd, 60 Lichfield Street, Walsall WS4 2BX, United Kingdom

Product name and form

Hanixol 50 mg Tablets.

Pharmaceutical Form

Tablets.

Round 7.4 mm yellowish tablet, scored.

Qualitative and quantitative composition

Each Tablet contains 50 mg of 6-mercaptopurine.

Excipients with known effect:

Lactose anhydrous: 59 mg per tablet.

For the full list of excipients, see section 6.1.

Active Ingredient Description
Mercaptopurine

Mercaptopurine is an inactive pro-drug which acts as a purine antagonist but requires cellular uptake and intracellular anabolism to thioguanine nucleotides for cytotoxicity. The mercaptopurine metabolites inhibit de novo purine synthesis and purine nucleotide interconversions. The thioguanine nucleotides are also incorporated into nucleic acids and this contributes to the cytotoxic effects of the active substance.

List of Excipients

Lactose anhydrous
Maize starch
Starch, pregelatinized
Stearic acid
Magnesium stearate

Pack sizes and marketing

Type III 20 ml amber glass bottle containing 25 tablets with a polypropylene child-proof cap and silica gel desiccant.

Marketing authorization holder

Fontus Health Ltd, 60 Lichfield Street, Walsall WS4 2BX, United Kingdom

Marketing authorization dates and numbers

PL 42924/0019

07/03/2019

Drugs

Drug Countries
HANIXOL Ireland, United Kingdom

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