MECOLZINE Suppository Ref.[50655] Active ingredients: Mesalazine

Source: Web Search  Revision Year: 2022  Publisher: FAES FARMA, S.A., Mรกximo Aguirre, 14, 48940 โ€“ Leioa, Spain

Product name and form

Mecolzine 500 mg suppositories.

Pharmaceutical Form

Suppository.

Torpedo-shaped suppository with greyish-white to slightly violet-reddish color.

Qualitative and quantitative composition

Each suppository contains 500 mg of mesalazine.

For the full list of excipients, see section 6.1.

Active Ingredient Description
Mesalazine

Mesalazine is an aminosalicylate. The mechanism of action of mesalazine is not fully understood, but appears to have a topical anti-inflammatory effect on the colonic epithelial cells. Mucosal production of arachidonic acid metabolites, both through the cyclooxygenase and lipoxygenase pathways, is increased in patients with chronic inflammatory bowel disease, and it is possible that mesalazine diminishes inflammation by blocking cyclooxygenase and inhibiting prostaglandin production in the colon.

List of Excipients

Hard fat.

Pack sizes and marketing

Suppositories are packaged in PVC/PE strips.

Each pack contains 12, 24, 60 and 100 suppositories.

Not all pack sizes may be marketed.

Any unused medicinal product or waste material should be disposed of in accordance with local requirements.

Marketing authorization holder

FAES FARMA, S.A., Mรกximo Aguirre, 14, 48940 – Leioa, Spain

Marketing authorization dates and numbers

MA1278/00301

Date of first authorization: 20-10-2020

Drugs

Drug Countries
MECOLZINE Cyprus, Ecuador, Malta

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