Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2017 Publisher: AstraZeneca UK Limited, 600 Capability Green, Luton, LU1 3LU, United Kingdom
Nexium I.V. 40 mg Powder for solution for injection/infusion.
| Pharmaceutical Form |
|---|
|
Powder for solution for injection/infusion. White to off-white porous cake or powder. |
Each vial contains esomeprazole 40 mg (as sodium salt).
Excipient(s) with known effect: This medicinal product contains <1 mmol sodium (23 mg) per 40 mg, i.e. essentially sodium free.
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Esomeprazole |
Esomeprazole is the S-isomer of omeprazole and reduces gastric acid secretion through a specific targeted mechanism of action. Esomeprazole is a weak base and is concentrated and converted to the active form in the highly acidic environment of the secretory canaliculi of the parietal cell, where it inhibits the enzyme H+ K+ -ATPase – the acid pump and inhibits both basal and stimulated acid secretion. |
| List of Excipients |
|---|
|
Disodium edetate |
5ml vial made of colourless borosilicate glass, type I. Stopper made of bromobutyl latex-free rubber, cap made of aluminium and a plastic flip-off seal.
Pack sizes: 1 vial, 10 vials.
Not all pack sizes may be marketed.
AstraZeneca UK Limited, 600 Capability Green, Luton, LU1 3LU, United Kingdom
PL 17901/0221
Date of first authorisation: 10 March 2005
Date of latest renewal: 10 March 2010
| Drug | Countries | |
|---|---|---|
| NEXIUM | Austria, Australia, Brazil, Canada, Cyprus, Germany, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Italy, Japan, Lithuania, Malta, Mexico, Nigeria, Netherlands, New Zealand, Poland, Romania, Singapore, Tunisia, Turkey, United Kingdom, United States |
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