Source: Health Sciences Authority (SG) Revision Year: 2019 Publisher: Manufactured by TAKEDA PHARMACEUTICAL COMPANY LIMITED, Hikari Plant, Yamaguchi, Japan. Repacked by KOKANDO CO. LTD, Toyama, Japan Imported by Takeda (Thailand) Ltd., Bangkok, Thailand
Vocinti (Tablet) 10 mg.
Vocinti (Tablet) 20 mg.
| Pharmaceutical Form | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Vocinti (Tablet) 10 mg: Each film-coated tablet contains 10 mg of vonoprazan (as 13.36 mg vonoprazan fumarate).
Vocinti (Tablet) 20 mg: Each film-coated tablet contains 20 mg of vonoprazan (as 26.72 mg vonoprazan fumarate).
For excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Vonoprazan |
Vonoprazan suppresses basal and stimulated gastric acid secretion at the secretory surface of the gastric parietal cell through inhibition of the H+, K+-ATPase enzyme system in a potassium competitive manner. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, vonoprazan has been characterized as a type of gastric proton-pump inhibitor, in that it blocks the final step of acid production. Vonoprazan does not require activation by acid. Vonoprazan may selectively concentrate in the parietal cells in both the resting and stimulated states. Vonoprazan binds to the active pumps in a noncovalent and reversible manner. |
| List of Excipients |
|---|
|
D-Mannitol * Macrogol 6000 is a name in the Japanese Pharmacopoeia. Its average molecular mass is approximately 8300. Therefore it is different from Macrogol 6000 in European Pharmacopoeia (Ph.Eur.) or Polyethylene Glycol 6000 in US National Formulary (NF) whose average molecular mass is 6000 and it is equivalent to Macrogol 8000 in Ph. Eur. and Polyethylene Glycol 8000 in NF. |
Polyvinyl chloride (PVC) film/Aluminum foil blister, one blister contains 10 tablets.
Manufactured by TAKEDA PHARMACEUTICAL COMPANY LIMITED, Hikari Plant, Yamaguchi, Japan.
Repacked by KOKANDO CO. LTD, Toyama, Japan
Imported by Takeda (Thailand) Ltd., Bangkok, Thailand
Vocinti 10 mg: Reg.No.1C 15049/61(NC)
Vocinti 20 mg: Reg.No.1C 15050/61(NC)
6 July 2018
| Drug | Countries | |
|---|---|---|
| VOCINTI | Singapore |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
