XEROPRIM Tablet Ref.[50586] Active ingredients: Sulfamethoxazole Trimethoprim

Source: Marketing Authorisation Holder  Publisher: Oethmaan Biosims (Pty) Ltd., 14 Komatie Road, Emmarentia, Johannesburg 2195

Product name and form

XEROPRIM tablets.

Pharmaceutical Form

White, round flat tablet bisected on one side.

Qualitative and quantitative composition

Each tablet contains:

Trimethoprim 80 mg
Sulphamethoxazole 400 mg

Preservative: Nipastat 0,025 % m/m.

Sugar free.

Active Ingredient Description
Sulfamethoxazole

Sulfamethoxazole competitively inhibits the utilisation of para-aminobenzoic acid in the synthesis of dihydrofolate by the bacterial cell resulting in bacteriostasis.
Trimethoprim

Trimethoprim is a dihydrofolate reductase inhibitor, inhibiting the conversion of bacterial dihydrofolic acid to tetrahydrofolic acid, required for the synthesis of some amino acids. Its effects are considerably greater on the cells of micro-organisms than on the mammalian cells.
List of Excipients

Magnesium stearate
Microcrystalline cellulose
Nipastat
Pregelatinised starch
Sodium carboxymethyl cellulose
Maize ฯƒtarch

Pack sizes and marketing

Packed into blisters and patient ready packs of 28’s, 56’s and 100’s and bottles of 20’s, 100’s and 500’s tablets.

Marketing authorization holder

Oethmaan Biosims (Pty) Ltd., 14 Komatie Road, Emmarentia, Johannesburg 2195

Marketing authorization dates and numbers

27/20.2/0077

18 January 2006

Drugs

Drug Countries
XEROPRIM South Africa
 
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