Active ingredients: Cefuroxime
Zinacef for Injection or Infusion.
Cefuroxime is a white to cream powder to which appropriate amounts of water are added to prepare an off-white suspension for intramuscular use or a yellowish solution for intravenous administration.
Vials contain either 250 mg, 750mg or 1.5g cefuroxime (as sodium).
The total quantity of sodium per vial is as follows:
|Zinacef strength||Amount of sodium per vial|
|250 mg||14 mg|
|750 mg||42 mg|
|1.5 g||83 mg|
Cefuroxime inhibits bacterial cell wall synthesis following attachment to penicillin binding proteins (PBPs). This results in the interruption of cell wall (peptidoglycan) biosynthesis, which leads to bacterial cell lysis and death.
* Only the 1.5g injection pack is marketed (the infusion pack is not)
Glaxo Operations UK Limited, 980 Great West Road,Brentford,TW8 9GS
GlaxoSmithKline UK, Stockley Park West, Uxbridge, Middlesex UB11 1BT
28 April 2002