Chemical formula: C₁₈H₂₂N₂ Molecular mass: 266.381 g/mol PubChem compound: 6726
Cyclizine is a histamine H1 receptor antagonist of the piperazine class which is characterised by a low incidence of drowsiness. It possesses anticholinergic and antiemetic properties. The exact mechanism by which cyclizine can prevent or suppress both nausea and vomiting from various causes is unknown.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R06AE03 | Cyclizine | R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AE Piperazine derivatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CYCLIZINE Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| VALOID Solution for injection | Health Products Regulatory Authority (IE) | MPI, EU: SmPC |
Cyclizine is an active ingredient of these brands:
Austria (AT)
Cyprus (CY)
Finland (FI)
Ireland (IE)
New Zealand (NZ)Singapore (SG)
South Africa (ZA)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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