Chemical formula: C₂₄H₂₈ClN₅O₃ Molecular mass: 469.97 g/mol PubChem compound: 10660
Dimenhydrinate is a theoclate salt of the ethanolamine derivative diphenhydramine. It exhibits reversible competitive antagonism with histamine for the capture of H1 receptors. It has anticholinergic (antimuscarinic) properties that explain the anti-emetic action of the drug in cases of labyrinthial irritation (nausea, vertigo), and the central suppression it causes.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R06AA11 | R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AA Aminoalkyl ethers | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| DIMENHYDRINATE Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| DIMENHYDRINATE Solution for injection / Suppositories | Health Products and Food Branch (CA) | MPI, CA: SPM | |
| DIMENHYDRINATE Tablet | FDA, National Drug Code (US) | MPI, US: SPL/Old |
Dimenhydrinate is an active ingredient of these brands:
Austria (AT)
Brazil (BR)
Canada (CA)Croatia (HR)
Cyprus (CY)
Finland (FI)
France (FR)
Hong Kong (HK)
Ireland (IE)
Israel (IL)Malta (MT)
Poland (PL)Spain (ES)
Turkey (TR)United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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