High molecular weight (4000) macrogols are long linear polymers which retain water molecules by means of hydrogen bonds. When administered by the oral route, they lead to an increase in volume of intestinal fluids.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A06AD15 | Macrogol | A Alimentary tract and metabolism → A06 Laxatives → A06A Laxatives → A06AD Osmotically acting laxatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| PEGLAX Powder for oral solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Macrogol is an active ingredient of these brands:
United States (US)
Australia (AU)Austria (AT)Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)Ecuador (EC)Estonia (EE)Finland (FI)
France (FR)
Hong Kong (HK)
Ireland (IE)
Japan (JP)Lithuania (LT)Malta (MT)
Netherlands (NL)New Zealand (NZ)
Poland (PL)
Romania (RO)Singapore (SG)South Africa (ZA)
Spain (ES)
Tunisia (TN)Turkey (TR)United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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