Ibenzmethyzine Other names: Procarbazine

Chemical formula: C₁₂H₁₉N₃O  Molecular mass: 221.299 g/mol  PubChem compound: 4915

Active ingredient description

Procarbazine, a methylhydrazine derivative, is a cytostatic agent with weak MAO inhibitor properties. Its exact mode of action on tumour cells is unknown.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L01XB01 Procarbazine L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XB Methylhydrazines
Discover more medicines within L01XB01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PROCARBAZINE Capsule Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
MATULANE Capsule FDA, National Drug Code (US) MPI, US: SPL/Old

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 366-70-1
CAS Substance: 671-16-9
DrugBank Drug: DB01168
KEGG Drug: D08423
PubChem Compound: 4915
RxNorm Ingredient: 8702
SNOMED-CT Concept: 387474003
Procarbazine (substance)
UNII Identifier: 35S93Y190K
PROCARBAZINE

Medicines

Ibenzmethyzine is an active ingredient of these brands:

United States (US)

  • MATULANE as PROCARBAZINE HYDROCHLORIDE

Canada (CA)

  • MATULANE as PROCARBAZINE HYDROCHLORIDE

Estonia (EE)

  • HODPRO as PROCARBAZINE HYDROCHLORIDE
  • NATULAN as Procarbazine hydrochloride

France (FR)

  • NATULAN as Procarbazine hydrochloride

Lithuania (LT)

Malta (MT)

  • NATULAN as Procarbazine hydrochloride

Netherlands (NL)

  • NATULAN as Procarbazine hydrochloride

Romania (RO)

  • NATULAN as Procarbazine hydrochloride

Spain (ES)

  • NATULAN as Procarbazine hydrochloride

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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