Chemical formula: C₂₈H₂₇NO₄S Molecular mass: 473.583 g/mol PubChem compound: 5035
As a selective oestrogen receptor modulator (SERM), raloxifene has selective agonist or antagonist activities on tissues responsive to oestrogen. It acts as an agonist on bone and partially on cholesterol metabolism (decrease in total and LDL-cholesterol), but not in the hypothalamus or in the uterine or breast tissues.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| G03XC01 | Raloxifene | G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03X Other sex hormones and modulators of the genital system → G03XC Selective estrogen receptor modulators |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| EVISTA Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
| EVISTA Film-coated tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Raloxifene is an active ingredient of these brands:
United States (US)
Australia (AU)Brazil (BR)
Canada (CA)
Ecuador (EC)
Estonia (EE)Hong Kong (HK)
Israel (IL)
Japan (JP)
Lithuania (LT)Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
South Africa (ZA)Tunisia (TN)
Turkey (TR)United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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