Rifapentine

Chemical formula: C₄₇H₆₄N₄O₁₂  Molecular mass: 877.031 g/mol  PubChem compound: 6323497

Active ingredient description

Rifapentine, a cyclopentyl rifamycin, is an antimycobacterial agent. Rifapentine inhibits DNA-dependent RNA polymerase in susceptible strains of Mycobacterium tuberculosis but not in mammalian cells. At therapeutic levels, rifapentine exhibits bactericidal activity against both intracellular and extracellular M. tuberculosis organisms.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J04AB05 Rifapentine J Antiinfectives for systemic use → J04 Antimycobacterials → J04A Drugs for treatment of tuberculosis → J04AB Antibiotics
Discover more medicines within J04AB05

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 61379-65-5
DrugBank Drug: DB01201
KEGG Drug: D00879
PubChem Compound: 6323497
RxNorm Ingredient: 35617
SNOMED-CT Concept: 108686006
Rifapentine (substance)
UNII Identifier: XJM390A33U
RIFAPENTINE

Medicines

Rifapentine is an active ingredient of these brands:

United States (US)

Estonia (EE)

Hong Kong (HK)

Singapore (SG)

South Africa (ZA)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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