Umeclidinium Other names: Umeclidinium bromide

Chemical formula: C₂₉H₃₄BrNO₂  Molecular mass: 428.595 g/mol  PubChem compound: 11519070

Active ingredient description

Umeclidinium is a long acting muscarinic receptor antagonist (also referred to as an anticholinergic). It is a quinuclidine derivative that is a muscarinic receptor antagonist with activity across multiple muscarinic cholinergic receptor subtypes. Umeclidinium bromide exerts its bronchodilatory activity by competitively inhibiting the binding of acetylcholine with muscarinic cholinergic receptors on airway smooth muscle.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R03BB07 R Respiratory system → R03 Drugs for obstructive airway diseases → R03B Other drugs for obstructive airway diseases, inhalants → R03BB Anticholinergics
Discover more medicines within R03BB07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
INCRUSE ELLIPTA Inhalation powder, pre-dispensed European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 869185-19-3
DrugBank Drug: DB09076
KEGG Drug: D10180
PubChem Compound: 11519070
RxNorm Ingredient: 1487512
SNOMED-CT Concept: 706899005
Umeclidinium bromide (substance)
UNII Identifier: GE2T1418SV
UMECLIDINIUM

Medicines

Umeclidinium is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

Spain (ES)

Tunisia (TN)

  • INCRUSE as UMECLIDINIUM BROMIDE

  • (combination) ANORO as UMECLIDINIUM BROMIDE

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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