Vitamin K1 Other names: Phytomenadione Phytylmenadione alpha-Phylloquinone Phytylmenadione Phylloquinone Phytonadione

Chemical formula: C₃₁H₄₆O₂  Molecular mass: 450.696 g/mol  PubChem compound: 5284607

Active ingredient description

The presence of vitamin K (i.e. vitamin K or substances with vitamin K activity) is essential for the formation within the body of prothrombin, factor VII, factor IX and factor X. Lack of vitamin K leads to an increased tendency to haemorrhage. When an antidote to an anticoagulant is necessary it is essential to use vitamin K1 itself, as vitamin K analogues are much less effective.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
B02BA01 Phytomenadione B Blood and blood forming organs → B02 Antihemorrhagics → B02B Vitamin K and other hemostatics → B02BA Vitamin K
Discover more medicines within B02BA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
KONAKION MM Solution (ampoules) Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
KONAKION MM PAEDIATRIC Solution (ampoules) Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 84-80-0
DrugBank Drug: DB01022
KEGG Drug: D00148
PubChem Compound: 5284607
RxNorm Ingredient: 8308
SNOMED-CT Concept: 65183007
Vitamin K and/or vitamin K derivative (substance)
UNII Identifier: S5Z3U87QHF
PHYTONADIONE, (E)-

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