ABECMA

Brand name authorized in: Ireland

Active ingredients

The drug ABECMA contains one active pharmaceutical ingredient (API):

1 Idecabtagene vicleucel
UNII 8PX1X7UG4D - IDECABTAGENE VICLEUCEL

Idecabtagene vicleucel is a chimeric antigen receptor (CAR)-positive T cell therapy targeting B-cell maturation antigen (BCMA), which is expressed on the surface of normal and malignant plasma cells. The CAR construct includes an anti-BCMA scFv-targeting domain for antigen specificity, a transmembrane domain, a CD3-zeta T cell activation domain, and a 4-1BB costimulatory domain. Antigen-specific activation of idecabtagene vicleucel results in CAR-positive T cell proliferation, cytokine secretion and subsequent cytolytic killing of BCMA-expressing cells.

Read about Idecabtagene vicleucel

Medication package inserts

Below package inserts are available for further reading:

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Summary of product characteristics (SPC)