ABECMA

This brand name is authorized in Estonia, Ireland, Poland

Active ingredients

The drug ABECMA contains one active pharmaceutical ingredient (API):

1 Idecabtagene vicleucel
UNII 8PX1X7UG4D - IDECABTAGENE VICLEUCEL

Idecabtagene vicleucel is a chimeric antigen receptor (CAR)-positive T cell therapy targeting B-cell maturation antigen (BCMA), which is expressed on the surface of normal and malignant plasma cells. The CAR construct includes an anti-BCMA scFv-targeting domain for antigen specificity, a transmembrane domain, a CD3-zeta T cell activation domain, and a 4-1BB costimulatory domain. Antigen-specific activation of idecabtagene vicleucel results in CAR-positive T cell proliferation, cytokine secretion and subsequent cytolytic killing of BCMA-expressing cells.

Read about Idecabtagene vicleucel

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
ABECMA Dispersion for infusion European Medicines Agency (EU) MPI, EU: SmPC

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: EE Ravimiamet Identifier(s): 1860140
Country: PL Rejestru Produktรณw Leczniczych Identifier(s): 100457776

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