ACTOPLUS MET

Brand name authorized in: United States

Active ingredients

The drug ACTOPLUS MET contains a combination of these active pharmaceutical ingredients (APIs):

1 Pioglitazone
UNII JQT35NPK6C - PIOGLITAZONE HYDROCHLORIDE

Pioglitazone effects may be mediated by a reduction of insulin resistance. Pioglitazone appears to act via activation of specific nuclear receptors (peroxisome proliferator activated receptor gamma) leading to increased insulin sensitivity of liver, fat and skeletal muscle cells in animals. Treatment with pioglitazone has been shown to reduce hepatic glucose output and to increase peripheral glucose disposal in the case of insulin resistance.

Read about Pioglitazone
2 Metformin
UNII 786Z46389E - METFORMIN HYDROCHLORIDE

Metformin is a biguanide with antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It does not stimulate insulin secretion and therefore does not produce hypoglycaemia.

Read about Metformin

Medication package inserts

Below package inserts are available for further reading:

Title
Type
Country
Structured product labeling (SPL/PLR)
US

Unique identifiers

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country
Identification scheme
Identifier(s)
US
FDA, National Drug Code
Identifier(s): 64764-155, 64764-158, 64764-310, 64764-510