ACTOPLUS MET

Found in: United States

Active ingredients

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Active Ingredient
Description
1

Pioglitazone effects may be mediated by a reduction of insulin resistance. Pioglitazone appears to act via activation of specific nuclear receptors (peroxisome proliferator activated receptor gamma) leading to increased insulin sensitivity of liver, fat and skeletal muscle cells in animals. Treatment with pioglitazone has been shown to reduce hepatic glucose output and to increase peripheral glucose disposal in the case of insulin resistance.

2

Metformin is a biguanide with antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It does not stimulate insulin secretion and therefore does not produce hypoglycaemia.

Product monographs

Monograph
Type
Country

Identifiers

Authority
Identifier(s)
FDA, National Drug Code (US)
Identifier(s): 64764-155, 64764-158, 64764-310, 64764-510