Brand name authorized in: South Africa
The drug ACUCO contains a combination of these active pharmaceutical ingredients (APIs):
Trimethoprim is a dihydrofolate reductase inhibitor which affects the nucleoprotein metabolism of micro-organisms by interference in the folic-folinic acid systems, inhibiting the conversion of bacterial dihydrofolic acid to tetrahydrofolic acid, required for the synthesis of some amino acids. Its effects are considerably greater on the cells of microorganisms than on the mammalian cells. Trimethoprim may be bactericidal or bacteriostatic depending on growth conditions.
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows: