ADEMPAS

This brand name is authorized in United States. It is also authorized in Australia, Austria, Brazil, Canada, Croatia, Cyprus, Estonia, Finland, France, Hong Kong SAR China, Ireland, Israel, Japan, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, Spain, Turkey, UK.

Active ingredients

The drug ADEMPAS contains one active pharmaceutical ingredient (API):

1	Riociguat UNII RU3FE2Y4XI - RIOCIGUAT
	Riociguat is a stimulator of soluble guanylate cyclase (sGC), an enzyme in the cardiopulmonary system and the receptor for nitric oxide (NO). Riociguat restores the NO-sGC-cGMP pathway and leads to increased generation of cGMP.
	Read more about Riociguat

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
ADEMPAS Film-coated tablet	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
C02KX05		C Cardiovascular system → C02 Antihypertensives → C02K Other antihypertensives → C02KX Antihypertensives for pulmonary arterial hypertension
Discover more medicines within C02KX05

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
AU	Pharmaceutical Benefits Scheme	10974N, 10975P, 10976Q, 10977R, 10984D, 10985E, 10989J, 10990K, 10995Q, 11001B, 11002C, 11008J, 11009K, 11010L, 11012N, 11013P, 11017W, 11018X, 11019Y, 11020B, 11024F, 11028K, 11030M, 11031N, 11035T, 11038Y, 11039B, 11040C, 11045H, 11046J, 11047K, 11048L, 11052Q, 11053R, 11054T, 11057Y, 11058B, 11059C, 11060D, 11061E
BR	Câmara de Regulação do Mercado de Medicamentos	538916010025301, 538916010025501, 538916010025701, 538916010025801, 538916010025901, 538916010026001, 538916010026101, 538916010026201
CA	Health Products and Food Branch	02412764, 02412772, 02412799, 02412802, 02412810
EE	Ravimiamet	1644375, 1644386, 1644397, 1644409, 1644410, 1644421, 1644432, 1644443, 1644454, 1644465, 1644476, 1644487, 1644498, 1644500, 1644511, 1699735, 1699746, 1699757, 1699768, 1699779
ES	Centro de información online de medicamentos de la AEMPS	113907004, 113907007, 113907010, 113907013
FI	Lääkealan turvallisuus- ja kehittämiskeskus	069347, 112191, 135090, 164827, 165799, 415368, 485304, 541846, 561780
FR	Base de données publique des médicaments	60025054, 60203795, 61875550, 64832942, 66086562
GB	Medicines & Healthcare Products Regulatory Agency	243980, 243985, 243994, 243998, 243999, 244007, 244009
HK	Department of Health Drug Office	63505, 63509, 63510, 63511, 63512
IE	Health Products Regulatory Authority	88599, 88690, 88692, 88694, 88695, 89068, 89069
IL	מִשְׂרַד הַבְּרִיאוּת	7574, 7575, 7578, 7768
JP	医薬品医療機器総合機構	2190034F1027, 2190034F2023, 2190034F3020
LT	Valstybinė vaistų kontrolės tarnyba	1073042, 1073043, 1073044, 1073045, 1073046, 1073047, 1073048, 1073049, 1073050, 1073051, 1073052, 1073053, 1073054, 1073055, 1073056, 1074977, 1074978, 1074979, 1074980, 1074981
NL	Z-Index G-Standaard, PRK	124656, 124664, 124672, 124680, 124699
NZ	Medicines and Medical Devices Safety Authority	16951, 16952, 16953, 16954, 16955
PL	Rejestru Produktów Leczniczych	100322670, 100322686, 100322692, 100322700, 100322717
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W63713001, W63714001, W63715001, W63716001, W63717001
SG	Health Sciences Authority	14678P, 14679P, 14680P, 14681P, 14682P
TR	İlaç ve Tıbbi Cihaz Kurumu	8699546090198, 8699546090204, 8699546090211, 8699546090228, 8699546090235, 8699546090242, 8699546090266, 8699546090273, 8699546090280, 8699546090297
US	FDA, National Drug Code	50419-250, 50419-251, 50419-252, 50419-253, 50419-254