ADREVIEW

Found in: Spain France United Kingdom United States

Active ingredients

UNII: P2TH1XYZ84 - IOBENGUANE I-123

Iobenguane is similar in structure to the antihypertensive drug guanethedine and to the neurotransmitter norepinephrine (NE). Iobenguane is, therefore, largely subject to the same uptake and accumulation pathways as NE. Iobenguane accumulates in adrenergically innervated tissues such as the adrenal medulla, salivary glands, heart, liver, spleen and lungs as well as tumors derived from the neural crest. By labeling iobenguane with the isotope iodine 123, it is possible to obtain scintigraphic images of the organs and tissues in which the radiopharmaceutical accumulates.

Medicine classification

ATC Code
Title
Class
Iobenguane (123I)
V Various → V09 Diagnostic radiopharmaceuticals → V09I Tumour detection → V09IX Other diagnostic radiopharmaceuticals for tumour detection

Product monographs

Monograph
Type
Country

Identifiers

Authority
Identifier(s)
FDA, National Drug Code (US)
Identifier(s): 17156-235
Base de données publique des médicaments (FR)
Identifier(s): 65884582
Centro de información online de medicamentos de la AEMPS (ES)
Identifier(s): 68722
Medicines & Healthcare Products Regulatory Agency (GB)
Identifier(s): 398499, 398503, 398506, 398510, 398514, 398517, 398526, 398529