AFSTYLA

Brand name authorized in: Austria Brazil Cyprus Spain Finland France Hong Kong Ireland Lithuania Netherlands New Zealand Poland Singapore

Active ingredients

The drug AFSTYLA contains one active pharmaceutical ingredient (API):

1 Lonoctocog alfa
UNII VQ723R7O8R - LONOCTOCOG ALFA

Lonoctocog alfa is a recombinant human protein that replaces the missing coagulation factor VIII needed for effective hemostasis. Lonoctocog alfa is a single polypeptide chain with a truncated B-domain that allows for a covalent bridge to link the factor VIII heavy and light chains. Lonoctocog alfa has demonstrated a higher VWF affinity relative to full-length rFVIII. VWF stabilizes factor VIII and protects it from degradation. Activated lonoctocog alfa has an amino acid sequence identical to endogenous FVIIIa.

Read about Lonoctocog alfa

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code
Group title
Classification
Coagulation factor VIII
B Blood and blood forming organs → B02 Antihemorrhagics → B02B Vitamin K and other hemostatics → B02BD Blood coagulation factors
Discover more medicines within B02BD02

Medication package inserts

Below package inserts are available for further reading:

Title
Type
Country
Summary of Product Characteristics (SPC)

Unique identifiers

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country
Identification scheme
Identifier(s)
BR
Câmara de Regulação do Mercado de Medicamentos
Identifier(s): 502620090009407, 502620090009507, 502620090009607, 502620090009707, 502620090009807
ES
Centro de información online de medicamentos de la AEMPS
Identifier(s): 1161158001, 1161158002, 1161158003, 1161158005
FI
Lääkealan turvallisuus- ja kehittämiskeskus
Identifier(s): 070563, 076792, 135654, 137797, 167588, 444932, 533147
FR
Base de données publique des médicaments
Identifier(s): 60944716, 61411315, 61906519, 64280351, 64477690, 66216027, 67710662
HK
Department of Health Drug Office
Identifier(s): 66199, 66200, 66201, 66202
LT
Valstybinė vaistų kontrolės tarnyba
Identifier(s): 1082000, 1082001, 1082002, 1082003, 1082004, 1082005, 1082006
NL
Z-Index G-Standaard, PRK
Identifier(s): 139254, 139262, 139270, 139289, 139297, 139300, 139319
NZ
Medicines and Medical Devices Safety Authority
Identifier(s): 18984, 19053, 19054, 19055, 19056, 19057, 19058
PL
Rejestru Produktów Leczniczych
Identifier(s): 100383890, 100383908, 100383914, 100383920, 100383937, 100383943, 100383950
SG
Health Sciences Authority
Identifier(s): 15820P, 15821P, 15822P, 15823P, 15824P