Brand name authorized in: Austria Brazil Cyprus Spain Finland France Hong Kong Ireland Lithuania Netherlands New Zealand Poland Singapore
The drug AFSTYLA contains one active pharmaceutical ingredient (API):
Lonoctocog alfa is a recombinant human protein that replaces the missing coagulation factor VIII needed for effective hemostasis. Lonoctocog alfa is a single polypeptide chain with a truncated B-domain that allows for a covalent bridge to link the factor VIII heavy and light chains. Lonoctocog alfa has demonstrated a higher VWF affinity relative to full-length rFVIII. VWF stabilizes factor VIII and protects it from degradation. Activated lonoctocog alfa has an amino acid sequence identical to endogenous FVIIIa.
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
Below package inserts are available for further reading:
This drug has been assigned below unique identifiers within the countries it is being marketed: