ATRIANCE

This brand name is authorized in Austria, Canada, Croatia, Estonia, Finland, France, Ireland, Lithuania, Netherlands, Poland, Romania, Spain, UK.

Active ingredients

The drug ATRIANCE contains one active pharmaceutical ingredient (API):

1
UNII 60158CV180 - NELARABINE
 

Nelarabine is a pro-drug of the deoxyguanosine analogue ara-G. Accumulation of ara-GTP in leukaemic blasts allows for preferential incorporation of ara-GTP into deoxyribonucleic acid (DNA) leading to inhibition of DNA synthesis. This results in cell death. Other mechanisms may contribute to the cytotoxic effects of nelarabine. In vitro, T-cells are more sensitive than B-cells to the cytotoxic effects of nelarabine.

 
Read more about Nelarabine

Medication package inserts

Below package inserts are available for further reading:

Document Type Information Source  
 ATRIANCE Solution for infusion MPI, EU: SmPC European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group Classification
L01BB07 Nelarabine L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01B Antimetabolites → L01BB Purine analogues
Discover more medicines within L01BB07

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
CA Health Products and Food Branch 02299925
EE Ravimiamet 1306763, 1826568, 1849585, 1879702
ES Centro de información online de medicamentos de la AEMPS 07403001
FI Lääkealan turvallisuus- ja kehittämiskeskus 039376, 078365
FR Base de données publique des médicaments 66034512
GB Medicines & Healthcare Products Regulatory Agency 122078, 391314
LT Valstybinė vaistų kontrolės tarnyba 1027574, 1088891
NL Z-Index G-Standaard, PRK 85030
PL Rejestru Produktów Leczniczych 100177250
RO Agenția Națională a Medicamentului și a Dispozitivelor Medicale W64498001, W64498002

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