BEQALZI

This brand name is authorized in United States.

Active ingredients

The drug BEQALZI contains one active pharmaceutical ingredient (API):

1
UNII 30R67U9KYS - SONROTOCLAX
 

Sonrotoclax is an inhibitor of B-cell lymphoma 2 (BCL-2) protein. Overexpression of BCL-2 in various cancers mediates cell survival and has been associated with chemotherapeutic resistance. Sonrotoclax binds to the BCL-2 protein, displacing pro-apoptotic proteins, thereby inducing apoptosis of cells. In nonclinical studies, sonrotoclax demonstrated cytotoxicity in cancer cells overexpressing BCL-2, with a series of intrinsic apoptotic events, including caspase activation.

 
Read more about Sonrotoclax

Medication package inserts

Below package inserts are available for further reading:

Document Type Information Source  
 BEQALZI Film-coated tablet MPI, US: SPL/PLR FDA, National Drug Code (US)

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
US FDA, National Drug Code 72579-015, 72579-017, 72579-020, 72579-022, 72579-025

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