BISOLNEX

This brand name is authorized in Netherlands

Active ingredients

The drug BISOLNEX contains one active pharmaceutical ingredient (API):

1 Noscapine
UNII TTN62ITH9I - NOSCAPINE HYDROCHLORIDE

Noscapine is a benzylisoquinoline alkaloid from plants of the poppy family, without painkilling properties. Noscapine is often used as an antitussive medication. Noscapine can increase the effects of centrally sedating substances such as alcohol and hypnotics. Noscapine, and its synthetic derivatives called noscapinoids, are known to interact with microtubules and inhibit cancer cell proliferation. Mechanisms for its antitussive action are unknown, although animal studies have suggested central nervous system as a site of action. Furthermore, noscapine causes apoptosis in many cell types and has potent antitumor activity against solid murine lymphoid tumors (even when the drug was administered orally) and against human breast and bladder tumors implanted in nude mice. Antifibrotic effect of noscapine based on novel mechanism, which it shows through EP2 prostaglandin E2 receptor-mediated activation of protein kinase A.

Read about Noscapine

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
R05DA07 Noscapine R Respiratory system → R05 Cough and cold preparations → R05D Cough suppressants, excl. combinations with expectorants → R05DA Opium alkaloids and derivatives
Discover more medicines within R05DA07

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: NL Z-Index G-Standaard Identifier(s): 16038223
Country: NL Z-Index G-Standaard, PRK Identifier(s): 13382

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