CIMZIA

This brand name is authorized in Austria, Australia, Brazil, Canada, Cyprus, Germany, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Japan, Lithuania, Netherlands, Poland, Romania, Tunisia, Turkey, United Kingdom, United States

Active ingredients

The drug CIMZIA contains one active pharmaceutical ingredient (API):

1 Certolizumab pegol UNII UMD07X179E - CERTOLIZUMAB PEGOL

Certolizumab pegol has a high affinity for human TNFα and binds with a dissociation constant (KD) of 90 pM. TNFα is a key pro-inflammatory cytokine with a central role in inflammatory processes. Certolizumab pegol was shown to neutralise membrane associated and soluble human TNFα in a dose-dependent manner. By inhibiting the action of TNFα, certolizumab pegol reduces inflammation and other symptoms in patients with rheumatoid arthritis. Read about Certolizumab pegol

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
CIMZIA Solution for injection	European Medicines Agency (EU)	MPI, EU: SmPC
Cimzia 200 mg solution for injection	Medicines & Healthcare Products Regulatory Agency (GB)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L04AB05	Certolizumab pegol	L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AB Tumor necrosis factor alpha (TNF-α) inhibitors
Discover more medicines within L04AB05

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 10137M, 10238W, 10892G, 10896L, 10897M, 10904X, 10905Y, 10909E, 11318Q, 11319R, 11320T, 11321W, 11322X, 11323Y, 11324B, 11325C, 11326D, 12005W, 12013G, 12027B, 12028C, 12040Q, 12063X, 3425G
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 525217050021917, 525217050022017
Country: CA	Health Products and Food Branch	Identifier(s): 02331675, 02465574
Country: DE	Bundesinstitut für Arzneimittel und Medizinprodukte	Identifier(s): 00996241, 01686991, 01751636, 01751978, 06907741, 06907758, 06935186, 07693331, 09245430, 09294291, 10709053, 10709076, 11032322, 11156159, 11514765, 11668132, 12450719, 12450731, 12466293, 12547382, 12547399, 12638044, 13168741, 13425669, 13425675, 13859161, 13859178, 13988964, 14025162, 14025179, 14053230, 14053247, 14055217, 14055223, 14307185, 14367402, 14420119, 14420125, 14445935, 14445964, 16168730, 16168753, 16169089, 16529613, 16808046, 16875628, 16875634
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): H3070113
Country: EE	Ravimiamet	Identifier(s): 1456107, 1456118, 1699320, 1744556, 1744567, 1744578, 1762916, 1762927, 1762938
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 109544001, 109544005, 109544008
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 060812, 066304, 552479
Country: FR	Base de données publique des médicaments	Identifier(s): 64386835, 66661714
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 173161, 335119, 378471
Country: HK	Department of Health Drug Office	Identifier(s): 61805, 67262
Country: IE	Health Products Regulatory Authority	Identifier(s): 88502, 88677
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 7383
Country: JP	医薬品医療機器総合機構	Identifier(s): 3999437G1022, 3999437G2029
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1051600, 1051601, 1072083, 1075875, 1084279, 1084280, 1084281, 1084282, 1084283, 1084284
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 137219, 143189, 92584
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100206939
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W54992001, W54992002
Country: TN	Direction de la Pharmacie et du Médicament	Identifier(s): 3113031H
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8699624950017
Country: US	FDA, National Drug Code	Identifier(s): 50474-710