CORTONE

This brand name is authorized in Japan

Active ingredients

The drug CORTONE contains one active pharmaceutical ingredient (API):

1 Cortisone
UNII 883WKN7W8X - CORTISONE ACETATE

Cortisone is a man-made version of a natural hormone called cortisol (corticosteroid hormone). It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug. Cortisol is converted by the action of the enzyme corticosteroid 11-beta-dehydrogenase isozyme 2 into the inactive metabolite cortisone, particularly in the kidneys. This is done by oxidizing the alcohol group at carbon 11 (in the six-membered ring fused to the five-membered ring). Cortisone is converted back to the active steroid cortisol by stereospecific hydrogenation at carbon 11 by the enzyme 11β-Hydroxysteroid dehydrogenase type 1, particularly in the liver. Cortisol decreases your body’s natural defensive response and reduces symptoms such as swelling and allergic-type reactions. This medication is used to treat conditions such as arthritis, blood/hormone/immune system disorders, allergic reactions, certain skin and eye conditions, breathing problems, and certain cancers.

Read about Cortisone

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: JP 医薬品医療機器総合機構 Identifier(s): 2452001F1036

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